# HbA1c (IFCC) in mmol/mol **URL:** \ **Category:** chemistry\ **Created:** [March 5, 2010, 4:44pm UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682 "2010-03-05T16:44:24Z")\ **Posts on this page:** 5\ **Page:** 1
**Author:** ![dbakkeren](https://forum.loinc.org/letter_avatar_proxy/v4/letter/d/ee7513/32.png) [@dbakkeren](https://forum.loinc.org/u/dbakkeren)\ **Post date:** [March 5, 2010, 4:44pm UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682/1 "2010-03-05T16:44:24Z")
This year a world wide program is started to express hemoglobin A1c/hemoglobin.total in mmol/mol. This means drastically different values will be reported tot docters and patients. Internationally a big campaign is started to notify docters, patients and all others concerned. Currently LOINC only contains hemoglobin a1/hemoglobin.total (LOINC 4548-4 or when performed by HPLC: 17856-6) expressed in % ; % Hgb. I can hardly believe that a LOINC code for this new assay/unit combination is not yet present in LOINC. Is this true? Together with the new HbA1c (IFCC) a derived measure will often be reported: the Average Glucose (AvG in mmol/l or g/dL, this is country specific) Also for these assays I haven’t found LOINC codes. Are parties so occupied in their communication with docters and patients that they forget about electronic communication … using LOINC codes? Dirk Bakkeren Clinical chemist Máxima Medisch Centrum, Veldhoven Netherlands ---
**Author:** ![kmercer](https://forum.loinc.org/letter_avatar_proxy/v4/letter/k/bb73d2/32.png) [@kmercer](https://forum.loinc.org/u/kmercer)\ **Post date:** [April 22, 2010, 6:30pm UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682/2 "2010-04-22T18:30:33Z")
We have created a LOINC code for this term , which will come out in the next release. 59261-8|Hemoglobin A1c/Hemoglobin.total|SFr|Pt|Bld|Qn|IFCC method The units are to be reported as umol/mole which is 10x more than a % and 1000 times more than a pure fraction (the moles cancel out). But the really important difference is the fact that the value done by the IFCC method would be about 40% lower than the current method (often referred to as NGSP - reported as a % and tied to the results of the big Diabetes study). So it is not just a matter of moving the decimal place- these are really different tests There are complexities regarding this test. Some of the instrument vendors are providing a way to report either or both the IFCC or the NGSP results- but doing this by via a conversion formula - not necessarily using the formal methods. In any case the code exists. The two terms you were looking for regarding estimated average glucose are in the current Relma/LOINC release- one is quite old. 27353-2|Estimated average glucose|MCnc|Pt|Bld|Qn|Estimated from glycated hemoglobin 53553-4|Estimated average glucose|SCnc|Pt|Bld|Qn|Estimated from glycated hemoglobin ---
**Author:** ![dbakkeren](https://forum.loinc.org/letter_avatar_proxy/v4/letter/d/ee7513/32.png) [@dbakkeren](https://forum.loinc.org/u/dbakkeren)\ **Post date:** [April 26, 2010, 3:26pm UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682/3 "2010-04-26T15:26:47Z")
Dear Kathy, The units you mention in your answer are not the correct units for the HbA1c (IFCC) method. The HbA1c (IFCC) is expressed in mmol (HbA1c)/mol (Hb) NOT in umol/mol. This has international agreement which really can’t be changed. Can you please confirm that the units in mmol/mol? Best regards Dr Dirk Bakkeren ---
**Author:** ![kmercer](https://forum.loinc.org/letter_avatar_proxy/v4/letter/k/bb73d2/32.png) [@kmercer](https://forum.loinc.org/u/kmercer)\ **Post date:** [April 27, 2010, 11:47am UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682/4 "2010-04-27T11:47:45Z")
Dirk, my apologies. What was posted was someone else’s text. The units for the new LOINC code will be mmol/mol, as you requested. ---
**Author:** ![system](https://forum.loinc.org/uploads/default/original/1X/dbab97ce9b2987d788a376e254fcaae249f3b672.png) [@system](https://forum.loinc.org/u/system)\ **Post date:** [June 23, 2023, 3:36pm UTC](https://forum.loinc.org/t/hba1c-ifcc-in-mmol-mol/682/5 "2023-06-23T15:36:23Z")